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Retroviruses

воскресенье 12 апреля admin 88

ret·ro·vi·rus

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Retroviruses are a family of viruses that are grouped together based on how they are structured and how they replicate within a host. Besides human immunodeficiency virus (HIV), the virus that causes AIDS, there a two other retroviruses that can cause human illness. One is called human T-lymphotropic virus type 1 (HTLV-1) and the other is. Are γ-retroviruses self-inactivating (SIN)? Plasmids that encode SIN γ-retrovirus lack most of the U3 region of the 3’ LTR and are primarily used in gene therapy research to reduce promoter interference and/or drive high expression of a transgene from an internal promoter.

ret'rō-vī'rŭs),

Retroviruses are potent disease agents, but they have also served as invaluable research tools in molecular biology. In 1979, the molecular biologist Richard Mulligan used a genetically altered retrovirus to trigger the production of hemoglobin in vitro by monkey kidney cells. His technique for using retroviruses to import alien genes into cells has been widely adopted. Medical researchers have also explored retroviral transport as a means of gene therapy. However, evidence suggesting that retroviruses may play a role in carcinogenesis raises questions as to the safety of their use in gene therapy. see oncogene.

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schematic of a retrovirus

ret·ro·vi·rus

(rĕt′rō-vī′rəs, rĕt′rə-vī′-)n.pl.ret·ro·vi·rus·es

Any of a family of viruses, many of which produce tumors, that contain RNA and reverse transcriptase, including HIV.

retrovirus

(ˈrɛtrəʊˌvaɪrəs) n

(Microbiology) any of several viruses whose genetic specification is encoded in RNA rather than DNA and that are able to reverse the normal flow of genetic information from DNA to RNA by transcribing RNA into DNA: many retroviruses are known to cause cancer in animals

ret•ro•vi•rus

(ˌrɛ trəˈvaɪ rəs, ˈrɛ trəˌvaɪ-)
n., pl. -rus•es.

any of various single-stranded RNA-containing viruses, of the family Retroviridae, that have a helical envelope and contain the enzyme reverse transcriptase, which enables genetic information from viral RNA to become part of host DNA.

ret`ro•vi′ral,adj.

ret·ro·vi·rus

(rĕt′rō-vī′rəs)

Any of a group of viruses containing RNA in which the RNA can convert to DNA inside a cell. Some retroviruses cause cancer in humans. The virus that causes AIDS is a retrovirus.

Noun

retrovirus - any of a group of viruses that contain two single-strand linear RNA molecules per virion and reverse transcriptase (RNA to DNA); the virus transcribes its RNA into a cDNA provirus that is then incorporated into the host cell

animal virus - an animal pathogen that is a virus

HTLV-1, human T-cell leukemia virus-1 - retrovirus causing T-cell leukemia

human immunodeficiency virus, HIV - the virus that causes acquired immune deficiency syndrome (AIDS); it replicates in and kills the helper T cells

retrovirus

retrovirus

[ˈretrəʊˌvaɪrəs]N → retrovirusm inv

retrovirus

ret·ro·vi·rus

n. retrovirus, virus que pertenece al grupo ácido ARN, algunos de los cuales son oncogénicos;

retrovirus

n retrovirus m
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